Biotransformations in Organic Chemistry

Biotransformations in Organic Chemistry
Springer; 6th Edition | September 28, 2011 | ISBN-10: 3642173926 | 434 pages | PDF | 4.97 MB

The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale.
This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts—principles of stereoselective transformations, enzyme properties and kinetics—the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C–C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques and modified or artificial enzymes, are treated in a separate section. A final chapter deals with thebasic rules for the safe and practical handling of biocatalysts.

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Ideas in Chemistry and Molecular Sciences: Advances in Synthetic Chemistry

Bruno Pignataro, "Ideas in Chemistry and Molecular Sciences: Advances in Synthetic Chemistry"


Publisher: Wiley-VCH
2010
ISBN: 3527325395
PDF
332 pages
3.7 MB



Written by some of the most talented young chemists in Europe, this text covers most of the groundbreaking issues in chemistry. It provides an account of the latest research results in European chemistry based on a selection of leading young scientists participating in the 2008 European Young Chemists Award competition. The contributions range from self-organization to new catalytic synthetic methodologies to organocatalysis. In addition, the authors provide a current overview of their field of research and a preview of future directions.

For organic, catalytic, natural products and biochemists.

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Tietz Fundamentals of Clinical Chemistry

Carl A. Burtis PhD, Edward R. Ashwood MD, David E. Bruns MD, "Tietz Fundamentals of Clinical Chemistry"

Saunders
2007
ISBN: 0721638651
976 pages
PDF
116 MB



A condensed, student-friendly version of Tietz Textbook of Clinical Chemistry, this text uses a laboratory perspective to provide you with the chemistry fundamentals you need to work in a real-world, clinical lab. Accurate chemical structures are included to explain the key chemical features of relevant molecules. Offering complete, accurate coverage of key topics in the field, it's everything that you expect from the Tietz name!



More than 500 illustrations and easy-to-read tables help you understand and remember key concepts.

Key words, learning objectives, and other student-friendly features reinforce important material.

Chapter review questions are included in an appendix to test your knowledge.

A two-color design makes it easier to read and easy to find important topics.

In-depth, reader-friendly content is appropriate for MT/CLS and MLT/CLT students and may also be used by laboratory practitioners, pathology residents, and others.



A new chapter on newborn screening discusses the basic principles, screening recommendations, inborn errors, methods, and interpretation of results.

A comprehensive glossary provides easy-to-find definitions of key terms.

An Evolve website provides regular updates of content, answers to review questions, and web links to related sites for further research and study.



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Mcqs in Biochemistry

G. Vidya Sagar, "Mcqs in Biochemistry"

Netlibrary Inc
2008
ISBN: 8122426271
300 pages
PDF
1 MB



Competitive Examinations are the order of the day. All Colleges conducting professional courses at PG level are admitting students based on common entrance examination, which is of objective type. In Pharmacy, M.Pharm admissions are based on qualifying the GATE enterance examination conducted by Govt. of India. In this book, The author has done good work in preparing several objective questions which help the students to face the subject in the examination with poise and confidence. The book is well balanced and consists of multiple choice questions from all the important topics like carbohydrate metabolism and other important Biochemical aspects. The typesetting and quality of printing is good. The author is also well experienced in taking up this type of work. I recommend this book to all the students preparing for GATE examination and also for Medical and Pharmacy College libraries.

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Clincial Chemistry: A Laboratory Perspective

Clincial Chemistry: A Laboratory Perspective

Publisher: F A Davis Co ISBN: 0803614985 edition 2007 PDF 605 pages 9,5 mb



Responding to the market need, Wendy Arneson and Jean Brickell have created a new style of textbook designed to excite your students' interest in clinical chemistry. Organized almost entirely around organ systems, this groundbreaking text teaches the concepts and principles of clinical chemistry through realistic situations and scenarios. The authors develo[ped this practical approach to encourage students to apply theoritical principles in the laboratory and to develop practical, critical-thinking skills.

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Clinical Studies in Medical Biochemistry

Robert H. Glew, Miriam D. Rosenthal, "Clinical Studies in Medical Biochemistry"

Oxford University Press, USA; 3rd edition (August 24, 2006) English 0195176871 392 pages PDF 5.52 MB



This text uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 33 cases are carefully selected to cover key concepts and common diseases. Each chapter provides a specific patient report that includes the relevant history, pertinent clinical laboratory data, physical findings, and subsequent diagnosis. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. In this third edition of the book, a new co-editor has aided in the substantially revised and more targeted selection of cases. The whole volume is now clearly focussed on intermediary metabolism and other topics central to biochemistry. There are new chapters on topics such as collagen structure, mitochondrial metabolism, and hyperhomocysteinemia and vascular disease. There is also more coverage of nutrional biochemistry, including new chapters on protein-calorie malnutrition, obesity, vitamin A deficiency, and iron metabolism.

The best cases were retained from the previous edition, and have been completely rewritten and updated to include recent advances in diagnostic biochemistry and the status of current therapies. Although the first edition was intended primarily for medical students, through the years the book has proven useful for a wide variety of students interested in the health science professions.


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Chemistry: An Illustrated Guide to Science

Chemistry: An Illustrated Guide to Science by: Derek Mcmonagle

Chelsea House Publications

Pages: 208 2006-08-30 ISBN 0816061637 PDF 5 MB



Chemistry: An Illustrated Guide to Science" is one of eight volumes of "Facts On File's" new "Science Visual Resources" set. Containing eight sections, a comprehensive glossary, a Web site guide, and an index, Chemistry is an ideal learning tool for students and teachers of science. Full-colour diagrams, graphs, charts, and maps on every page illustrate the essential elements of the subject, while parallel text provides key definitions and step-by-step explanations. The eight sections include: "Atomic Structures" - provides an overview of the very basic structure of physical matter.

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Bioinorganic Chemistry: Cellular Systems and Synthetic Model

Eric C. Long, “Bioinorganic Chemistry: Cellular Systems and Synthetic Model”

Oxford University Press 2009 ISBN-10: 0841269750 264 Pages PDF 23,8 MB



Bioinorganic Chemistry: Cellular Systems and Synthetic Models includes chapters describing cutting-edge work by renowned researchers in the field that fall within two main areas of current bioinorganic chemistry: (1) the study of cellular systems and processes that occur inside cells that are impacted by inorganic elements, e.g., biosynthetic pathways leading to the production of vital metal-containing enzymes and proteins including iron-sulfur clusters, hemes, and cytochrome c oxidase; metal homeostasis (Zn2+ in E. coli); and new strategies to examine DNA targeting by metal-based drugs using, as an example, the clinically-employed bleomycin class of antitumor agents, and (2) sophisticated new inorganic model systems, many of which escape the traditional approach of trying to use structural mimics of the native systems to produce functional mimics and instead use a more conceptual approach to the use of bioinorganic models to understand the native system or to develop useful synthetic molecules. In the former area, unlike most traditional efforts in bioinorganic chemistry that have been devoted to studies of the structures and functions of metal centers located within individual metal-containing proteins, the topics described in this volume seek to describe whole systems of interaction between multiple interacting biomolecules that are impacted by inorganic species. In the latter area, along with chapters devoted to more traditional ligand systems and inorganic reactivities, peptide- and protein-like ligand systems are emphasized creating agents that: lead to novel structures and morphologies, de novo designed systems that model biological Hg binding, and unique DNA-targeted agents that mimic the activities of nucleic acid-targeted natural products and proteins. Together, these chapters provide examples of the exciting current work in two important areas in the exciting field of bioinorganic chemistry
 
 
 
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Schaum's Outline of Biochemistry, Third Edition

Schaum's Outline of Biochemistry, Third Edition

Publisher: McGraw-Hill pages: 506 2010 ISBN: 0071472274 PDF 10,5 mb





This step-by-step outline steers you logically, expertly, and clearly through biochemistry. It saves you study time and helps you get better grades by focusing on the core information you really need to know! This easy-to-follow study guide can help you ace biochemistry! Clear and well-organized, it gives you all the information you needand avoids confusing, extraneous material that you don't need!

 
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Physical Chemistry of Macromolecules: Basic Principles and Issues by S. F. Sun

Physical Chemistry of Macromolecules: Basic Principles and Issues by S. F. Sun




Publisher: Wiley-Interscience; 2 edition (January 28, 2004)
ISBN: 0471281387
Pages: 584
PDF
8.26 MB





Integrating coverage of polymers and biological macromolecules into a single text, Physical Chemistry of Macromolecules is carefully structured to provide a clear and consistent resource for beginners and professionals alike. The basic knowledge of both biophysical and physical polymer chemistry is covered, along with important terms, basic structural properties and relationships. This book includes end of chapter problems and references, and also: Enables users to improve basic knowledge of biophysical chemistry and physical polymer chemistry. Explores fully the principles of macromolecular chemistry, methods for determining molecular weight and configuration of molecules, the structure of macromolecules, and their separations.
 
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Forensic Chemistry

David E. Newton, "Forensic Chemistry"

Facts on File
2009
ISBN: 0000
336 pages
PDF
1,6 MB



This book offers a fascinating look at the field of forensic chemistry.From the study of explosives and bodily fluids to drug analysis and fingerprints, chemical methods have played a major role in crime investigation in the last few decades. "Forensic Chemistry" examines the many ways these scientific techniques have infiltrated crime investigation in today's world.This accessible book examines the chemical characteristics of fuels and explosives, as well as arson-related methods; other ways of identifying criminals through chemical processes, including blood and bodily fluid analyses, the chemical characteristics found in fibers and hair, and latent and DNA fingerprinting; and the chemical properties of drug analysis. Biographical information on important researchers in the field is also included. "Forensic Chemistry" is ideal for readers interested in the chemical methods used behind the crime scene.The chapters include: The Origins of Forensic Science; Fingerprinting; Forensic Serology; Toxicology and Drug Testing; Arson and Explosives Investigations; and, DNA Fingerprinting.

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General, Organic, and Biological Chemistry

General, Organic, and Biological Chemistry


Author(s):Janice G. Smith

Publisher:McGraw-Hill

Date:2010-01

Format:PDF

Language:English

ISBN10:0073026573



Product Description:

This new GOB textbook is written with the same student-focused, direct writing style that has been so successful in the Smith: Organic Chemistry text. Smith writes with a bulleted approach that delivers need-to-know information in a succinct style for today's students. Armed with an excellent illustration program full of macro-to-micro art, as well as many applications to biological, medical, consumer, and environmental topics, this book is a powerhouse of learning for students.



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The Practice of Medicinal Chemistry by Camille Georges Wermuth (3th Edition)

The Practice of Medicinal Chemistry, Second Edition (The Practice of Medicinal Chemistry)


By Camille Georges Wermuth

* Publisher: Academic Press

* Number Of Pages: 624

* Publication Date: 2003-03-19

* ISBN-10 / ASIN: 0127444815

* ISBN-13 / EAN: 9780127444819



Product Description:

Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists with little or no background in medicinal chemistry. These chemists must acquire a good knowledge of medicinal chemistry during their first years in the pharmaceutical/drug discovery industry. This book aims to be their practical handbook - a complete guide to the drug discovery process.



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Fundamentals of Medicinal Chemistry by Gareth Thomas

Gareth Thomas, "Fundamentals of Medicinal Chemistry"


John Wiley & Sons 2003
ISBN-10: 0470843063
302 Pages
PDF
1,9 MB







Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style.The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product.

The text assumes little in the way of prior biological knowledge. relevant biology is included through biological topics, examples and the Appendices.



Incorporates summary sections, examples, applications and problems

Each chapter contains an additional summary section and solutions to the questions are provided at the end of the text

Invaluable for undergraduates studying within the chemical, pharmaceutical and life sciences


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Advanced Practical Medicinal Chemistry

Ashutosh Kar "Advanced Practical Medicinal Chemistry"


New Age International (P) Ltd.
2004
ISBN: 8122415393
332 pages
PDF
2,5 MB



The present compendium on Advanced Practical Medicinal Chemistry is designed specifically to serve as a text-cum-reference book not only intended for the advanced undergraduate and graduate students of Pharmacy specializing in pharmaceutical chemistry but also for the bulk-drug industrial researchers and academics who work intimately with medicinal compounds. It mainly comprises of four comprehensive chapters. First chapter is entirely devoted to Safety in Chemical Laboratory, which is an absolute must for each medicinal chemist. Second chapter is on Drug Synthesis and concentrates on three vital aspects, namely : conceptualization of a synthesis, reaction variants, and stereochemistry. Third chapter exclusively deals with Performing the Reactions and entails the wide range of latest laboratory techniques used in a good chemical laboratory to facilitate synthesis of drugs.



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Medicinal Chemistry of Bioactive Natural Products by Xiao-Tian Liang

Medicinal Chemistry of Bioactive Natural Products by: Xiao-Tian Liang, Wei-Shuo Fang.(Editors)




Publisher: Wiley
ISBN: 0471660071
April 2006
Pages: 460
PDF
5.5 MB



Current discoveries and research into bioactive natural products Medicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies--developed for natural products--with an emphasis on the structure activity relationship of bioactive natural products. The topics have been carefully chosen on the basis of relevance to current research and to importance as clinicially useful agents.



Rather than attempting to be a comprehensive encyclopedia of bioactive natural products, Medicinal Chemistry of Bioactive Natural Products guides the reader to the key developments in the field. By providing not only practical detail but a historical perspective on the chemistry and biology of the compounds under consideration, the book serves as a handy resource for researchers in their own work developing pharmaceuticals, and as an inspiring introduction for young scientists to the dynamic field of bioactive natural products research.




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An Introduction to Medicinal Chemistry by Graham L. Patrick

An Introduction to Medicinal Chemistry by Graham L. Patrick




Publisher: Oxford University Press, USA (June 8, 1995)
ISBN: 0198558724
Pages: 352
PDF



This illustrated text provides undergraduate and postgraduate students with an accessible introduction to medicinal chemistry. It covers basic principles and background, and then describes the general tactics and strategies employed in developing an effective drug. Through the use of numerous examples, it highlights both the difficulties faced by the medicinal chemist and the great power and potential of rational drug design. This book is suitable for undergraduates on courses in chemistry (2nd and 3rd year) and medicinal chemistry (1st and 2nd year), and postgraduate chemists beginning work in pharmaceutical research.



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Physical Chemistry, Second Edition

Robert G. Mortimer, «Physical Chemistry, Second Edition»


Academic Press
ISBN: 0125083459
2 edition (March 2000)
1128 pages
PDF
136 Mb



This new edition of Robert G. Mortimer's Physical Chemistry has been thoroughly revised for use in a full year course in modern physical chemistry. In this edition, Mortimer has included recent developments in the theories of chemical reaction kinetics and molecular quantum mechanics, as well as in the experimental study of extremely rapid chemical reactions. While Mortimer has made substantial improvements in the selection and updating of topics, he has retained the clarity of presentation, the integration of description and theory, and the level of rigor that made the first edition so successful.



* Emphasizes clarity; every aspect of the first edition has been examined and revised as needed to make the principles and applications of physical chemistry as clear as possible.

* Proceeds from fundamental principles or postulates and shows how the consequences

of these principles and postulates apply to the chemical and physical phenomena being studied.

* Encourages the student not only to know

the applications in physical chemistry but to understand where they come from.

* Treats all topics relevant to undergraduate physical chemistry
Thanks to the original uploader!






DOWNLOAD BOTH PARTS FROM RAPIDSHARE:




PART A HERE
 
PART B HERE

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Physical Chemistry of Macromolecules: Basic Principles and Issues by S. F. Sun

Physical Chemistry of Macromolecules: Basic Principles and Issues by S. F. Sun


Publisher: Wiley-Interscience; 2 edition (January 28, 2004)
ISBN: 0471281387
Pages: 584
PDF
8.26 MB





Integrating coverage of polymers and biological macromolecules into a single text, Physical Chemistry of Macromolecules is carefully structured to provide a clear and consistent resource for beginners and professionals alike. The basic knowledge of both biophysical and physical polymer chemistry is covered, along with important terms, basic structural properties and relationships. This book includes end of chapter problems and references, and also: Enables users to improve basic knowledge of biophysical chemistry and physical polymer chemistry. Explores fully the principles of macromolecular chemistry, methods for determining molecular weight and configuration of molecules, the structure of macromolecules, and their separations.







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Physical Chemistry: Kinetics

Physical Chemistry: Kinetics


Taylor & Francis
2006-02-21
ISBN: 0815340893
Pages: 138
PDF
15 MB



This is a new undergraduate textbook on physical chemistry by Horia Metiu published as four separate paperback volumes. These four volumes on physical chemistry combine a clear and thorough presentation of the theoretical and mathematical aspects of the subject with examples and applications drawn from current industrial and academic research. By using the computer to solve problems that include actual experimental data, the author is able to cover the subject matter at a practical level. The books closely integrate the theoretical chemistry being taught with industrial and laboratory practice. This approach enables the student to compare theoretical projections with experimental results, thereby providing a realistic grounding for future practicing chemists and engineers. Each volume of Physical Chemistry includes MathematicaRG and MathcadRG Workbooks on CD-ROM.



Metiu's four separate volumes-Thermodynamics, Statistical Mechanics, Kinetics, and Quantum Mechanics-offer built-in flexibility by allowing the subject to be covered in any order.



These textbooks can be used to teach physical chemistry without a computer, but the experience is enriched substantially for those students who do learn how to read and write MathematicaRG or MathcadRG programs. A TI-89 scientific calculator can be used to solve most of the exercises and problems





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