Showing posts with label Pharmacology. Show all posts
Showing posts with label Pharmacology. Show all posts

Medical Pharmacology at a Glance, 4th Edition

"Medical Pharmacology at a Glance" is one of the most renowned undergraduate texts in the field of medical pharmacology. Following on from the success of the previous three editions, Professor Michael Neal, one of the great teachers of medical pharmacology, has extensively revised and updated the fourth edition to take account of the rapid developments in the field. This incredibly useful book summarises the core principles of the mode of action of drugs and puts this information within the context of body systems and specific clinical problems. The author discusses the mechanisms of action of each drug, indicating the therapeutics of choice for specific conditions. "Medical Pharmacology at a Glance" follows the now familiar, easy-to-use double page spread format of the at a Glance series. Each section contains a clear illustration depicting the major drugs and their interaction within a particular body system and a concise account of the topic. Key features of the fourth edition include: new material on anti-platelet drugs in the cardiovascular section; new section on immunological drugs; new material on general anaesthetic and anti-viral drugs; and the use of Recommended International Non-proprietary Names (rINN) for drugs. "Medical Pharmacology at a Glance" is ideal for pharmacology revision and for use during clinical placements. It is an essential buy for medical students and scientists requiring a succinct and lucid account of medical pharmacology.

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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy





Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy


Lippincott Williams & Wilkins
2007
ISBN: 0781783550
985 pages
CHM
64 MB



This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system. Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development. The fully searchable online text and an image bank are available on thePoint. "Doody's Core Titles 2009."

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Foye's Principle of Medicinal Chemistry (6th Edition)

Thomas L. Lemke, David A. Williams, "Foye's Principles of Medicinal Chemistry, 6 Edition"


LW & W
2007
ISBN: 0781768799
1377 pages
PDF
57 MB



The Sixth Edition of this well-known text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist.

A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men's and women's health problems. Also new to this edition: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures.

Case studies from previous editions and answers to this edition's case studies are available online at thePoint.

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Drug Transporters (Handbook of Experimental Pharmacology, Volume 201) By Martin F. Fromm, Richard B. Kim

* Publisher: Springer


* Number Of Pages: 430

* Publication Date: 2010-12-01

* ISBN-10 / ASIN: 364214540X

* ISBN-13 / EAN: 9783642145407





It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.



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Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability



Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability


Wiley-VCH
ISBN: 3527601473
Year 2003
English
579pages
PDF
size: 8,99Mb



The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten.

In 21 chapters readers can benefit from the key working knowledge of today's leading pharmaceutical companies, including Pfizer, AstraZeneca, and Roche. Drug developers from industry and academia present all the factors governing drug bioavailability, complete with practical examples and real-life data.

Part I focuses on in vitro and in vivo measurements of physicochemical properties, such as membrane permeability and ionization. Part II discusses solubility and gastrointestinal absorption, while the third part is devoted to metabolism and excretory mechanisms. The much revised and expanded part IV surveys current in silico approaches to predict drug properties needed to estimate the bioavailability of any new drug candidate. The final part shows how poor bioavailability may be improved by various approaches during the development process.

No other publication offers the same level of treatment on this crucial topic in modern drug development. Download
 
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Goodman & Gilman's: The Pharmacological Basis of Therapeutics (11th Edition)

Goodman and Gilman's The Pharmacological Basis of Therapeutics by Laurence L. Brunton, John S. Lazo, and Keith L. Parker




Hardcover: 1984 pages

Publisher: McGraw-Hill Professional

Language: English



ISBN: 0071422803



"The 11th edition of Goodman & Gilman continues to be the most comprehensive and authoritative single source on the pharmacology of drugs. The first edition was published by Alfred Gilman and Louis Goodman in 1941. It soon became known as the bible of pharmacology and, even though editorship and chapter authorships have changed continuously from edition to edition, this remains the gold standard of pharmacology textbooks....The print version should be on the reference shelf and the digital version on the computer desktop of all practicing pharmacologists, pharmacists, and physicians"



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Goodman and Gilman's The Pharmacological Basis of Therapeutics by Laurence L. Brunton, John S. Lazo, and Keith L. Parker




Hardcover: 1984 pages

Publisher: McGraw-Hill Professional

Language: English



ISBN: 0071422803



"The 11th edition of Goodman & Gilman continues to be the most comprehensive and authoritative single source on the pharmacology of drugs. The first edition was published by Alfred Gilman and Louis Goodman in 1941. It soon became known as the bible of pharmacology and, even though editorship and chapter authorships have changed continuously from edition to edition, this remains the gold standard of pharmacology textbooks....The print version should be on the reference shelf and the digital version on the computer desktop of all practicing pharmacologists, pharmacists, and physicians"



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Goodman and Gilman's The Pharmacological Basis of Therapeutics by Laurence L. Brunton, John S. Lazo, and Keith L. Parker




Hardcover: 1984 pages

Publisher: McGraw-Hill Professional

Language: English



ISBN: 0071422803



"The 11th edition of Goodman & Gilman continues to be the most comprehensive and authoritative single source on the pharmacology of drugs. The first edition was published by Alfred Gilman and Louis Goodman in 1941. It soon became known as the bible of pharmacology and, even though editorship and chapter authorships have changed continuously from edition to edition, this remains the gold standard of pharmacology textbooks....The print version should be on the reference shelf and the digital version on the computer desktop of all practicing pharmacologists, pharmacists, and physicians"



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Modern Pharmacology with Clinical Applications

Modern Pharmacology with Clinical Applications Modern Pharmacology with Clinical Applications


Publisher: Lippincott Williams & Wilkins
ISBN: 0781737621
2003
PDF
802 pages
16,7 mb



Building on the strengths of previous editions, the sixth edition of Modern Pharmacology With Clinical Applications continues to provide an up-to-date and comprehensive textbook for students of pharmacology. Focusing on the clinical application of drugs within a context of the major principles of pharmacology, this text supplies both students and faculty with an introduction to modern pharmacotherapeutics. Written by experts in the field, the text remains concise enough to focus on the essentials of the subject while providing enough detail to ensure accuracy. Whether you are a student in medicine, osteopathy, dentistry, pharmacy, or advanced nursing, this book is written, organized, and edited to provide a clear and succinct guide to modern pharmacology
 
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Color Atlas of Pharmacology





"Color Atlas of Pharmacology" by Heinz Luellmann

Thieme Medical Publishers
414 pages
English
2005, 3 edition
ISBN: 313781703X
PDF
10,9 MB



Updated with the most important new substances and scientific developments, the third edition of The Color Atlas of Pharmacology makes it easier than ever for students, nurses, and practicing physicians to keep up with the latest developments in this constantly changing field. Featuring a user-friendly layout, jargon-free language, and more than 160 spectacular color charts and illustrations.





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Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs

Enno Freye, Joseph V. Levy, "Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs: A comprehensive review on their mode of action, treatment of abuse and intoxication"


Publisher: Springer
ISBN: 9048124476
edition 2009
PDF
300 pages
10.1 mb



Finally - a book that covers all aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB, written by two experts in their field. The use of these drugs remains a continuous threat in health and medical care delivery, and this book will be an essential asset to the physician who may have to face the evaluation of patients whose use of these drugs compromises an effective treatment plan for other health issues.



The book has been conceived to fill the void in existing physician reference materials, and provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance.



While detailed scientific information is obtainable in other major articles, the book's straightforward format and style, along with its illustrations, will make for easy reading as emphasis is put on information specifically related to drugs that occur most abused in today’s society. The information provided is based on clinical practice rather than pure experimental data, which will give the physician more effective tools useful in their daily practice. Many mechanisms of action of abuse are described in detail and references are provided to direct the reader to further sources for additional information.



As a special feature, the book incorporates uncluttered tables and charts, which result in immediate clarification of the mode of action on the central nervous system and the reason for misuse, thus avoiding usual long and fatiguing text in common reference books. The book aims to give the reader a clear and concise plan on what to do when being faced with an overdose situation.




A well-organized Table of Contents rapidly leads the reader from general pharmacological issues to the specific overdose syndrome and its management. Additionally, significant emphasis is placed on the practical do's and don’ts for physicians, with special reference to the predictive signs of aberrant drug-related behavior and the identification of the drug diverter by using urine drug screening.



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Clinical Physiology and Pharmacology: The Essentials






Farideh Javid, Janice McCurrie, "Clinical Physiology and Pharmacology: The Essentials"

Wiley
2008-12-12
ISBN: 0470518529
356 pages
PDF
1,6 MB



This book is an accessible collection of case study scenarios ideal for physiology and pharmacology revision for pharmacy, medical, biomedical science, clinical science and healthcare students.



Clearly structured and organized by major organ system, the book emphasises ways in which key signs and symptoms of disease inform diagnosis and the choice of treatment, together with the relevant pharmacological mechanisms. Each chapter has a clinical focus and includes clear learning outcomes, key points and model answers with detailed explanations designed to enhance students’ understanding of the physiology and pharmacology underpinning each case study scenario.



50 topics are covered and the cases presented include an extensive range of psychological, neurological, endocrine, cardiovascular, respiratory, renal, gastrointestinal and reproductive disorders, their symptoms, complications and usual treatment along with the actions and uses of some widely- used drugs.

* An essential revision text designed to help students apply their theoretical knowledge to real-life cases


* Realistic case studies focusing on commonly occurring conditions and diseases

* Model answers throughout

* Learning outcomes provided at the beginning of each chapter

* Key learning points presented in the cases follow each model answer

* Helps students to understand the relevance and clinical implications of the topics studied in physiology and pharmacology courses

* Reinforces major concepts and definitions

* Includes a glossary with a full list of drugs and disorders to support the text.



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Monika Schäfer-Korting - Drug Delivery (Handbook of Experimental Pharmacology)

Monika Schäfer-Korting - Drug Delivery (Handbook of Experimental Pharmacology)


Publisher: Springer
2010-01-01
ISBN: 3642004768
PDF
480 pages
6.30 MB



In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.







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Antiviral Strategies (Handbook of Experimental Pharmacology)

Antiviral Strategies (Handbook of Experimental Pharmacology)


379 pages
Springer; 1 edition (January 1, 2009)
ISBN-10: 3540790853
PDF
8,7 Mb



A crucial issue for antiviral therapy is the fact that all antiviral substances rapidly select for resistance; thus, monitoring and overcoming resistance has become a most important clinical paradigm of antiviral therapy. This calls for cautious use of antiviral drugs and implementation of combination therapies. In parallel, efforts in drug discovery have to be continued to develop compounds with novel mode-of-action and activity against resistant strains. This book reviews the current status of antiviral therapy, from the roads to development of new compounds to their clinical use and cost effectiveness. Individual chapters address in more detail all available drug classes and outline new approaches currently under development.





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Therapeutic Antibodies (Handbook of Experimental Pharmacology) By Yuti Chernajovsky, Ahuva Nissim

Therapeutic Antibodies (Handbook of Experimental Pharmacology) By Yuti Chernajovsky, Ahuva Nissim


Publisher: Springer
13-12-2007
ISBN: 3540732586
380 pages
5.04 Mb



Antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions and are becoming the molecules of choice for further combination therapies and cell engineering. Current developments and clinical successes are summarized by experts in the drug development field. A must read for immunologists, clinical scientists and novel drug developers.




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Comparative and Veterinary Pharmacology

Fiona Cunningham, Jonathan Elliott, Peter Lees, "Comparative and Veterinary Pharmacology (Handbook of Experimental Pharmacology, Volume 199)"


Publisher: S-nger
2010
ISBN: 3642103235
PDF
348 pages
2.9 MB



The topics addressed in this volume of comparative and veterinary pharmacology, as a series of succinct state of the art reviews, illustrate both the commonality and differences between drug pharmacodynamics and pharmacokinetics in animals and man and demonstrate the potential impact of drug use in animals on human health and the environment. Genetic modification of animals and the benefits this has brought to understanding human disease and the production of drugs for use in man is considered and the potential of new technologies for improving the treatment of animal disease explored.





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Handbook of Experimental Pharmacology, Vol. 194: Sensory Nerves

Brendan J. Canning, Domenico Spina, "Handbook of Experimental Pharmacology, Vol. 194: Sensory Nerves"


Springer
2009
ISBN: 3540790896
624 pages
PDF
6 MB



The intention of this book is to provide a comprehensive and contemporary review of the biology of sensory nerves. In keeping with the theme of the Handbook series, an emphasis will be placed on the actions of drugs, transmitters and autacoids that initiate or inhibit sensory nerve activation (through actions on ion channels and receptors at their peripheral terminals) or modulate the release or actions of the transmitters released from the central terminals of sensory nerves. Based on extensive supportive evidence in the literature, it is our view that many diseases are characterised by alterations in sensory nerve function (eg pain, cardiovascular disease, and migraine). It is our belief that this book will be unique, as it will comprehensively cover the role of sensory nerves across many therapeutic areas.



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Foye's Principle of Medicinal Chemistry (6th Edition)



Thomas L. Lemke, David A. Williams, "Foye's Principles of Medicinal Chemistry, 6 Edition"


LW & W
2007
ISBN: 0781768799
1377 pages
PDF
57 MB



The Sixth Edition of this well-known text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist.

A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men's and women's health problems. Also new to this edition: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures.




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